Just published by the National Acedemy of Sciences
http://www.pnas.org/content/107/3/961.full.pdf+html
"Unfortunately, it has become increasingly clear that most of the mutation load is associated with mutations with very small effects distributed at unpredictable locations over the entire genome, rendering the prospects for long-term management of the human gene pool by genetic counseling highly unlikely for all but perhaps a few hundred key loci underlying debilitating monogenic genetic disorders (such as those focused on in the present study).
Thus, the preceding observations paint a rather stark picture. At least in highly industrialized societies, the impact of deleterious mutations is accumulating on a time scale that is approximately the same as that for scenarios associated with global warming—perhaps not of great concern over a span of one or two generations, but with very considerable consequences on time scales of tens of generations. Without a reduction in the germline transmission of deleterious mutations, the mean phenotypes of the residents of industrialized nations are likely to be rather different in just two or three centuries, with significant incapacitation at the morphological, physiological, and neurobiological levels."
In short; the accumulative mutations generated by our breeding are too slow to get us past all the genetic deterioration that is occuring on a molecular level due to diseases defects and other things we are transmiting to one another.
We will not be evolving and it's quite likely none of earth's other macrobes will either.
We're all facing doom. (Very slow boring doom, like a glacier coming at your house from ten miles away, but DOOMED!!!!!)
Mendel 2 Darwin 0
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